Most bacterial infections (approx 80%) are biofilm based, so the assumption going in is that when an infection is present, it’s likely to be biofilm based.

NAC (N-acetyl-cysteine) breaks disulfide bonds. It’s often useful for sinusitis for this reason. It’s the active ingredient in mucomyst, and is given to patients with Cystic Fibrosis, to break up the thick mucous that they have to work to bring up out of their lungs. It is a great biofilm disrupter (there are plenty more I will get into through the next couple months). NAC is the precursor to glutathione which is why supplementing with glutathione is so great for the lungs and sinuses also.

Everyone needs a different dose. I usually suggest starting with 400mg twice a day and increase from there as needed. You want to do biofilm disruptors 2 weeks before starting antifungals and then during and after the anti-fungal or antibacterial treatment is over.